writing research proposal about cytokines in prgnant women associated with preeclampsia & sickle cell disease

Order Description

First, I need to cover all the following points in my research proposal in a perfect way.
1- Definition of cytokines.
2-Types of cytokines included the cells where these are secreted & produced.
3-Roles of cytokines on diagnosis a diseases, how they are inceased, decreased, or no effect. Please, provide some examples.
4-preeclampsia toxemia of pregnancy (introduction).
5-problems, implications & complications of preeclampsia toxemia pathology among pregnant women & their child.
6-Problems of early detection of preeclampsia toxemia.
7-sickle cell disease pathology, implications & complications.
8-implications & complications of preeclampsia toxemia with sickle cell disease together.
9-Trails of cytokines in early detection of preeclampsia toxemia.
10-Roles of cytokines to differentiate severity among sickle cell disease pregnant patients.
11-try to provide two table, one table for preeclampsia & second table for sickle cell disease to show most related & effective cytokines regarding their measurement
levels that causing problems, implications, & complications for both ( Preeclampsia toxemia & sickle cell disease).
12- give overview for both diseases ( preeclampsia toxemisa & sickle cell diseases) in kingdom of saudi arabia (in my countary).
13-Double pathology in pregnant women with both preeclampsia toxemia & sickle cell disease, is very complicated & make the pregnant women at very high risk & it is
very crucial to be able to detect. preeclampsia toxemia in pregnant women with sickle cell disease as early as possible to avoid implications & complications of this
two diseases.
14- no study in the literature have been created out on preeclampsia toxemia pregnant women who they have with sickle cell disease. So, the objectiveis that to
evaluate the roles of specific types of cytokines in early detection of preeclampsia toxemia pregnant women who they have with sickle cell disease.
15-methodology: Four gifferent groups of pregnant women will be included.
first group: 50 pregnant women with normal pregnancy as controls.
second group: 50 pregnant women with preeclampsia toxemia & sickle cell disease.
third group: 50 pregnant women with preeclampsia toxemia only.
fourth group: 50 pregnant women with sickle cell disease only.
The sample: approximately 5 ml of blood sample will be included.Serum will be separated & stored for estimation of cytokines.